About Scala

Scala Biodesign is developing ScalaOS, a next-generation protein design software platform that is transforming how scientists engineer proteins across therapeutics, diagnostics, materials, food, and sustainable chemistry.

ScalaOS unites physics-based modeling, AI, and evolutionary data in one intuitive environment, enabling R&D teams to design stable, high-performing proteins. By making computational design accessible to any scientist, it accelerates innovation in drug discovery, enzyme development, and biomanufacturing.

Originating from research at the Weizmann Institute of Science, Scala works with global leaders in pharmaceuticals, biotechnology, chemistry, and food production to advance protein design worldwide.

Founded in 2022 and backed by top-tier venture capital investors, Scala is growing rapidly and building a team to bring its platform to scientists everywhere.

About the Role

We are looking for a computational protein designer to join our multidisciplinary team of structural biologists, protein engineers, and software engineers; a team player who is excited to work in a small startup atmosphere, interact with scientists from varied companies and backgrounds, and take part in turning scientific breakthroughs into valuable products with a positive impact on humankind. 

Key Responsibilities

As part of our team you will develop, test and apply cutting-edge computational protein design methods to address challenging protein engineering problems: 

• Support computational design projects in collaboration with industrial partners from start to end on very tight timelines.
• Develop, test and troubleshoot new computational protein design algorithms.
• Interact with our partners’ scientific teams and learn their needs.
• Deep dive into the biochemistry and structure of various proteins.
• Stay current with the latest advancements in protein design.
• Apply machine learning models for protein engineering.

Qualifications

• PhD in protein engineering, antibody engineering, enzymology, biocatalysis or structural biology.
• Prior experience in experimental protein engineering or computational protein design.
• Proficiency in protein structural analysis and structure-function relationships.
• Flexible schedule, including occasional evening and weekend availability.
• Advantage: Industry or post-doc experience in antibody engineering, biocatalysis or medicinal chemistry.

Soft skills:

• Strong communication and collaboration skills.
• Fast learner and proven ability to master new domains.
• Excellent time management and multitasking skills.
• Ability to work effectively under pressure and meet tight deadlines.
• Great attention to details.
• Can-do attitude, pushing to get the job done.

How to Apply

Please send your CV to the following email addresses:

shira@scala-bio.com

shiran@scala-bio.com